Born August 8, 1901, in South Dakota, Lawrence attended state university before pursuing graduate studies. He chose to study physics on the advice of Merle Tuve-a childhood friend who was also destined to become a famous physicist. Lawrence enrolled in graduate school at the University of Minnesota in 1922 to study under W. F. G. Swann. As Swann was wooed first to the University of Chicago and then to Yale, Lawrence followed. He graduated with his Ph.D. from Yale University in 1925, where he soon took on a teaching post. In 1928 he headed west to become associate professor of physics at the University of California, Berkeley, where he built up the Radiation Laboratory with university funds and with financial help from private sources and where he would remain for most of his professional career. In 1939, he received the Nobel Prize in Physics for his pioneering work with cyclotrons. He would also earn a reputation in the 1930s as a top scientist-administrator overseeing scores of Rad Lab staff and young physicist cyclotroneers, and securing funding for Laboratory research. By the outbreak of the Second World War, Lawrence had made Berkeley a major center for nuclear physics.
Lawrence thought that it was merely a matter of time before the United States was drawn into the war, and he wanted the government to mobilize its scientific forces as rapidly as possible. Early in 1941, he began to consider using the electromagnetic method to separate the uranium-235 isotope to be used in a uranium bomb. He proposed using a mass spectrometer, converted from use in his 37-inch cyclotron to separate larger, purer samples of uranium-235 for study and, eventually, to use the process to derive the lighter isotope on a large scale. Lawrence dubbed his new device a "calutron" in honor of the University of California. Excited by the prospects, Lawrence launched a campaign to speed up uranium research. He met with Vannevar Bush, director of the National Defense Research Committee, warning that Germany was undoubtedly making progress and that the uranium committee overseeing government support of research was moving too slowly. Bush appointed him an advisor to the committee, a move that quickly resulted in funding for research on the electromagnetic method as well as plutonium work at Berkeley.
Although some observers doubted the likelihood that this method could produce uranium-235 on a large enough scale, Lawrence and his team had such success separating uranium isotopes that Bush expressed the hope in March 1942 that electromagnetic separation might produce enough enriched uranium for a bomb by 1944. In November 1942, electromagnetic separation was one of the two methods-along with gaseous diffusion-chosen for the uranium enrichment process. Research on beam resolution and magnet size and placement led Lawrence and his group to propose an arrangement of huge electromagnetic coils connected by a busbar in an oval racetrack configuration, as seen from above. Forty-eight gaps in the racetrack between the coils would each contain two vacuum tanks. Actual separation of the uranium isotopes would occur in the vacuum tanks. Construction of the first racetracks at the Y-12 Electromagnetic Plant in Oak Ridge, Tennessee, began in February 1943. Lawrence and his team were intimately involved throughout the design, construction, and operation of the Y-12 facility. Despite early optimism about the electromagnetic method, the first tracks were plagued with problems, and enrichment proceeded more slowly than expected. Ultimately, however, the technique proved to be the most fruitful method during the war for the production of weapons-grade uranium.
Lawrence, as head of the Rad Lab, played important roles in other major aspects of the Manhattan Project. Research at the lab by the chemist Glenn T. Seaborg identified element 94, which he later named plutonium, and proved that plutonium-239 was 1.7 times more likely than uranium-235 to fission. This indicated the possibility of producing large amounts of the fissionable plutonium in a uranium pile using plentiful uranium-238, and then separating it chemically. By late 1941, Lawrence was suggesting that plutonium might provide the shortest route to a weapon. In addition, Lawrence was a friend and colleague of the theoretical physicist J. Robert Oppenheimer, who came to Berkeley in 1929. Lawrence helped involve Oppenheimer, who became director of the Los Alamos laboratory, in initial discussions on the physics of the bomb.
Lawrence was first and foremost a physicist, but it was as a leader and promoter where he was perhaps most influential. As the historians Richard Hewlett and Oscar Anderson note:
Lawrence's progress [on electromagnetic separation up to February 1942] had indeed been spectacular, but even more impressive was his style. His daring, courage, and irrepressible optimism were contagious. He inspired his staff to sweat over tedious jobs with no thought of time, his superiors in the university to cut red tape, and his seniors in Washington to see heady visions of an early weapon. When Bush visited Berkeley in February, he found the atmosphere in the laboratory "stimulating" and "refreshing."
After the war, Lawrence remained an important advocate of and participant in nuclear research and weapons development. He was among the first to understand that the extraordinary costs of research in the new, post-war field would require government support. As the director of the Rad Lab, he continued its cutting edge efforts in particle physics. He remained involved in weapons work, including the development of the hydrogen bomb, and he helped found a second weapons laboratory at Livermore, California. Both the Rad Lab and the new weapons laboratory would come to bear his name: the Lawrence Berkeley National Laboratory and Lawrence Livermore National Laboratory. Lawrence remained director of the Rad Lab until his untimely death on August 27, 1958.
Los Carmelitas descalzos obtuvieron un Breve apostólico de Paulo V para edificar conventos de su Orden en cualquier parte de la Cristiandad; fue este el primero que fundaron en la última parte del Monte Quirinal el año de 1606.
La iglesia se fundó en 1605 como una capilla dedicada a san Pablo para los carmelitas descalzos. La propia orden dotó de fondos a la obra del edificio hasta el descubrimiento en las excavaciones de la escultura conocida como el Hermafrodita Borghese. Scipione Borghese se apropió de ella, pero a cambio, y quizá para compensar su pérdida de influencia debido a la muerte de su tío y patrón, financió el resto de la obra de la fachada y prestó a la orden a su arquitecto, Giovanni Battista Soria. Estas concesiones, sin embargo, sólo se llevaron a efecto en 1624, aunque la obra se acabó dos años más tarde.
Después de la victoria católica en la batalla de la Montaña Blanca en 1620, que hizo retroceder la Reforma en Bohemia, la iglesia fue consagrada de nuevo a la Virgen María. Una imagen maltrecha había sido recuperada del ámbito de aquella batalla por Fray Domingo de Jesús María, de dicha Orden, de las ruinas de la casa de campo de un noble cristiano bohemio, a la cual se le atribuyó la victoria, llamándola Santa María de la Victoria. La imagen fue llevada a Roma por Fray Domingo, depositándose en Santa María la Mayor en presencia de Gregorio XV.
El nombre de Santa María de la Victoria, se dio ulteriormente, en conmemoración por haber reconquistado el emperador Fernando I la ciudad de Praga en 1671. Estandartes turcos capturados en el Sitio de Viena de 1683 cuelgan en la iglesia, como parte de este tema victorioso.
La iglesia es la única estructura diseñada y completada por el arquitecto del Barroco temprano, Carlo Maderno, aunque el interior padeció un fuego en 1833 y requirió una restauración. Su fachada, sin embargo, fue erigida por Soria en vida de Maderno (1624-1626), mostrando la inconfundible influencia de la cercana Santa Susanna de Maderno.
Su interior tiene una sola nave, amplia, bajo una bóveda segmentada baja, con tres capillas laterales interconectadas detrás de arcos separados por colosales pilastras corintias con capiteles dorados que apoyan un rico entablamento. Revestimientos de mármol que contrastan entre sí están enriquecidos con ángeles y putti de estuco blanco y dorado en bulto redondo. El interior fue enriquecido progresivamente después de la muerte de Maderno; su bóveda fue pintada al fresco en 1663 con temas triunfales dentro de compartimentos con marcos ficticios: La Virgen María triunfa sobre la Herejía y Caída de los ángeles rebeldes ejecutados por Giovanni Domenico Cerrini.
Sin duda, parte de la fama de este templo se debe a albergar una de las obras maestras del Barroco, la capilla Cornaro, espectacular y teatral espacio presidido por el grupo escultórico que representa el Éxtasis de Santa Teresa, de Gian Lorenzo Bernini, quizá la obra más conocida de este autor en el campo de la escultura. En la capilla situada frente a esta, dedicada a San José, se encuentra un grupo escultórico que representa el tema del Sueño de San José, obra del escultor Domenico Guidi, que se inspira en la obra de Bernini delante de la cual se halla.1
Different cyclotron size: a) Lawrence ́s first one, b) Venezuela First one (courtesy of Dorly Coehlo), c) Fermi National Laboratory at CERN. And size matters, and Cyclotrons win as best hospital candidates due to Reactors are bigger, harder and difficult to be set in a hospital installation. Can you imagine a nuclear reactor inside a health installation? Radiation Protection Program will consume all the budget available. Size, controlled reactions, electrical control, made cyclotrons easy to install, and baby cyclotrons come selfshielded so hospital don ́t need to spend money in a extremely large bunker. Now on, we are going to talk about our first experience with the set up of a baby cyclotron for medical uses inside the first PET installation in Latin America. “Baby” means its acceleration “D” diameters are suitable to be set inside a standard hospital room dimensions, with all its needs to be safetly shielded for production transmision and synthetized for human uses for imaging in Nuclear Medicine PET routine. When we ask why Cyclotrons are better than reactors for radioisotopes production to be used in Medicine, we also have to have in mind that they has: 1. Less radioactive waste 2. Less harmful debris
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